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[[File:Restaurants in Richmond.png|300px|thumb|The Richmond Public Library (Library Tower, one of the tallest buildings in Virginia, in the background)]][[File:Guggenheim Store Front|thumb|Left to right: The Jersey City Bank (New Jersey) and the Rosenberg Gallery]]
Pattern of recurrence of ovarian clear cell carcinoma in Japanese patients: A single institution experience.
Clear cell carcinoma (CCC) of the ovary is a rare malignancy and is usually refractory to chemotherapy. The aim of the study was to evaluate the histological pattern of recurrence, treatment modalities and survival in Japanese patients. This was a single institution retrospective study. A total of 24 patients with CCC treated between 1989 and 2005 were identified in the institution's registry. Fifty-seven per cent of the patients were in FIGO stage I (n=14) and 43% were in stage II (n=10). A majority of patients underwent complete macroscopic resection (n=15, 62%), and most of the patients had received platinum and taxane based adjuvant chemotherapy (n=17, 71%). The median time to recurrence after initial treatment was 14 months (range, 1-102 months). The major histology of recurrence was in serous (n=17), endometrioid (n=3) or mixed (n=4) type. Patients with recurrence had received more adjuvant chemotherapy (82 vs 57%, p=0.005). The median survival time was 34 months, and the actuarial 5-year survival rates were 52% and 33% in the low and high grade group, respectively. The median survival time was not associated with FIGO stage, age, grade and status of capsule 0b46394aab